Treatment In Pregnancy for Hepatitis C: The TiP-HepC Registry
CGHE launched the TiP-HepC project on December 3rd at the International Viral Hepatitis Elimination Meeting (IVHEM). In the video on the right, Dr. Neil Gupta, Chief Technical Officer for the Coalition for Global Hepatitis Elimination, presents an abstract on the TiP-HepC project at IVHEM.
Contribute cases to TiP-HepC registry here
Background
Hepatitis C virus (HepC) antenatal screening is now recommended in the US and is increasingly the standard of care globally. However, there are no current interventions to reduce perinatal HepC transmission. Virologic suppression via the use of direct-acting antiviral (DAA) medications during pregnancy may reduce risk of mother-to-child HepC transmission, but there is very limited data regarding the safety and efficacy profile of DAAs for mother-infant pairs and off-label use of DAAs is determined on a case-by-case basis.
The Treatment In Pregnancy for Hepatitis C: The TiP-HepC Registry project is an initiative of the Coalition for Global Hepatitis Elimination (CGHE) at the Taskforce for Global Health and supported by the Centers for Disease Control and Prevention.
Request for Collaboration
CGHE is seeking partners and collaborators for the TiP-HepC project to:
- Contribute existing data on outcomes of mothers and infants exposed to DAA medications in pregnancy
- Provide ideas, support, or case enrollment for a prospective registry to document outcomes of mothers and infants exposed to DAA medications in pregnancy
- Join a “Community of Practice” to learn about current evidence and efforts in the treatment of HepC for pregnancy women
For questions contact:
Dr. Neil Gupta, Coalition for Global Hepatitis Elimination, ngupta-consultant [at] taskforce.org

Contribute data to TiP-HepC registry
The TiP-HepC registry is collecting retrospective data on the outcomes of mother– infant pairs exposed to DAAs during pregnancy in routine clinical practice will be solicited and collected from participating clinical providers, health-care facilities, HCV treatment programmes, and other clinical practices worldwide.