Seroepidemiology and risk factors of hepatitis C virus infection in East Azerbaijan, Iran: A population-based Azar Cohort study

default

Seroepidemiology and risk factors of hepatitis C virus infection in East Azerbaijan, Iran: A population-based Azar Cohort study

Authors

Pouri, A. A.,Ghojazadeh, M.,Pourasghari, B.,Baiaz, B.,Hamzavi, F. S.,Somi, M. H.

Citation
2019
Caspian Journal of Internal Medicine

10

3
326-331
Type
Cross-sectional
Virus targets
Hepatitis C
Interventions
Screening and diagnosis
Testing
Setting
National
Target populations
General Population
Country of development
Iran (Islamic Republic of)
Target location
Iran (Islamic Republic of)
DOI
10.22088/cjim.10.3.326
Testing strategy
Laboratory-based antibody test,Laboratory-based PCR/RNA (confirmatory) test
Laboratory-based antibody test
Laboratory-based PCR/RNA (confirmatory) test
Countries of included studies
Iran (Islamic Republic of)

Health outcomes

Number new diagnoses

Testing strategy

Laboratory-based antibody test,Laboratory-based PCR/RNA (confirmatory) test

Abstract

Background: Hepatitis C virus (HCV) is a blood-borne virus. It is a major global public health problem and can cause both acute and chronic hepatitis. The aim of this study was to report the epidemiological features of HCV infection and risk factors based on the data from Azar Cohort, East Azerbaijan province, Iran. Method(s): The population of this study comprised the people in the age range of 35-70 years from Azar Cohort, East Azerbaijan province, Iran. The study was conducted between 2015 and 2016. Based on cluster sampling, 4, 949 people were selected and invited to complete the questionnaire and perform the tests. Blood samples collected in this study were analyzed to detect the presence of antibodies against HCV using enzyme immunoassay (ELISA) Kit. The positive samples were re-tested by qualitative HCV-RNA polymerase chain reaction. All data were analyzed using SPSS version 19.0 software. Result(s): The mean age of the participants was 49.15+/-9.02 years. Of these participants, 54.3% (n=2686) were females. Seven people (0.14%) were detected as HCV positive and the highest frequency was seen in the age range of 40-50 (0.16%). There was a statistical significant relationship between history of hospitalization (P=0.02) and history of abnormal urine (P=0.01) with the frequency of HCV infection. Conclusion(s): The findings of this study indicated that the frequency of hepatitis C virus infection is 0.14% in the general population of Azar Cohort. Copyright © 2019 Babol University of Medical Sciences. All rights reserved.

Page updated

22 Jan 2021