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  2. Evidence base

Evidence base

The objective of the evidence base is to disseminate the best available information to promote the implementation of effective HBV and HCV prevention, testing, and treatment interventions to achieve elimination goals. The evidence base is a repository of systematic reviews on priority topics, such as hepB birth dose and hepatitis action plans. The evidence base is a searchable database of the individual references identified in each systematic review. Synthesis briefs that summarize the key findings and implications of each systematic review are available.

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Evidence base

All evidence

The full evidence base includes all systematic reviews, guidelines, and policies identified by the HepB birth dose and action plan systematic reviews.

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Action plan

The Action Plan Evidence Based includes the results of a systematic review of global, regional, national, and sub-national action plans for hepatitis B and C control and elimination. 

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Birth dose

The Birth Dose Evidence Base includes the results of a systematic review of other systematic reviews and guideline documents on the implementation of hepatitis B birth dose vaccination.

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HCV testing

The HCV Testing Evidence Base includes the results of a systematic review of studies that report on HCV testing algorithms and associated HCV public health outcomes (i.e. initiation of treatment). 

HepB birth dose synthesis

To help digest the rich Hepatitis B Birth Dose evidence base, we developed a synthesis brief. In this brief, you can find the list of references in the evidence base and an overview of their findings on effectiveness and cost-effectiveness of the birth dose, as well as a summary of the barriers to implementation and mitigating solutions described across the articles.
HepB birth dose synthesis

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Photos on home page by Tayvessa Wilson, Conor Ashleigh, and Zunaid Murshed Paiker

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