Dr Marian Major


Chief Virologist
Center for Drug Evaluation and Research (CDER), US Food and Drug Administration (FDA)
United States of America

Dr. Major is a virologist who currently holds the position of Chief, Laboratory of Hepatitis Viruses, Division of Viral Products, CBER/FDA. She obtained a Ph.D. from the University of Warwick, U.K. Dr. Major has been studying vaccine approaches for the prevention of HCV infection since 1994. She was one of the first people to show that natural infection from HCV can elicit protective T cell responses, opening the door for further vaccine development. She has written several reviews on the progress of HCV vaccines; completed a pivotal meta-analysis of HCV vaccine studies in chimpanzees; and showed, using an in silico model, that a vaccine against HCV would reduce transmission among people who inject drugs without necessarily achieving sterilizing immunity. The lab’s research findings have been published in international, peer-reviewed journals, and Dr. Major has co-authored several book chapters and review articles on HCV. As a result of her research, Dr. Major is a co-inventor on four patents: one on HCV peptide vaccines (2004), the second on HCV neutralization (2013), the third on an HCV neutralizing antibody (2016), and a fourth on HCV neutralizing epitopes, antibodies and methods (2017).


Marian Major