United States of America

United States of America

Hepatitis B

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Prevalence of chronic HBV (HBsAg+)

National
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Value (%) Year Type Source
0.38 (0.29 - 0.49) 1994 Survey/reported Wasley A et al, 2010
0.27 (0.20 - 0.35) 2006 Survey/reported Wasley A et al, 2010
0.3 (0.20 - 0.40) 2012 Survey/reported Roberts H et al, 2016
0.23 (0.18 - 0.28) 2015 Modelled WHO
0.3 (0.20 - 0.30) 2016 Modelled Razavi-Shearer et al, 2018
0.27 (0.24 - 0.30) 2013 Modelled Schweitzer et al, 2015
0.34 (0.30 - 0.38) 2019 Modelled IHME, GBD 2019 (accessed 2020)
0.37 (0.32 - 0.42) 2018 Modelled IHME, GBD 2019 (accessed 2022)
0.37 (0.33 - 0.42) 2017 Modelled IHME, GBD 2019 (accessed 2022)
0.38 (0.34 - 0.43) 2016 Modelled IHME, GBD 2019 (accessed 2022)
0.4 (0.35 - 0.44) 2015 Modelled IHME, GBD 2019 (accessed 2022)
0.4 (0.35 - 0.45) 2014 Modelled IHME, GBD 2019 (accessed 2022)
0.41 (0.36 - 0.46) 2013 Modelled IHME, GBD 2019 (accessed 2022)
0.42 (0.37 - 0.47) 2012 Modelled IHME, GBD 2019 (accessed 2022)
0.43 (0.38 - 0.48) 2011 Modelled IHME, GBD 2019 (accessed 2022)
0.44 (0.39 - 0.49) 2010 Modelled IHME, GBD 2019 (accessed 2022)
0.44 (0.39 - 0.50) 2009 Modelled IHME, GBD 2019 (accessed 2022)
0.46 (0.40 - 0.51) 2008 Modelled IHME, GBD 2019 (accessed 2022)
0.47 (0.41 - 0.53) 2007 Modelled IHME, GBD 2019 (accessed 2022)
0.48 (0.42 - 0.54) 2006 Modelled IHME, GBD 2019 (accessed 2022)
0.49 (0.43 - 0.55) 2005 Modelled IHME, GBD 2019 (accessed 2022)
0.49 (0.43 - 0.56) 2004 Modelled IHME, GBD 2019 (accessed 2022)
0.5 (0.44 - 0.56) 2003 Modelled IHME, GBD 2019 (accessed 2022)
0.51 (0.44 - 0.57) 2002 Modelled IHME, GBD 2019 (accessed 2022)
0.51 (0.45 - 0.57) 2001 Modelled IHME, GBD 2019 (accessed 2022)
0.51 (0.45 - 0.58) 2000 Modelled IHME, GBD 2019 (accessed 2022)
0.52 (0.45 - 0.58) 1999 Modelled IHME, GBD 2019 (accessed 2022)
0.53 (0.46 - 0.59) 1998 Modelled IHME, GBD 2019 (accessed 2022)
0.54 (0.47 - 0.60) 1997 Modelled IHME, GBD 2019 (accessed 2022)
0.55 (0.47 - 0.61) 1996 Modelled IHME, GBD 2019 (accessed 2022)
0.55 (0.48 - 0.62) 1995 Modelled IHME, GBD 2019 (accessed 2022)
0.55 (0.48 - 0.62) 1994 Modelled IHME, GBD 2019 (accessed 2022)
0.55 (0.48 - 0.63) 1993 Modelled IHME, GBD 2019 (accessed 2022)
0.56 (0.48 - 0.63) 1992 Modelled IHME, GBD 2019 (accessed 2022)
0.56 (0.49 - 0.64) 1991 Modelled IHME, GBD 2019 (accessed 2022)
0.57 (0.49 - 0.64) 1990 Modelled IHME, GBD 2019 (accessed 2022)
0.37 (0.32 - 0.41) 2019 Modelled IHME, GBD 2019 (accessed 2022)
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Children under-5 years
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Value (%) Year Type Source
0.04 (0.03 - 0.05) 2015 Modelled WHO
0.03 (0.02 - 0.04) 2019 Modelled IHME, GBD 2019 (accessed 2020)
0.05 (0.03 - 0.06) 2019 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.06) 2018 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.07) 2017 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.06) 2016 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.06) 2015 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.06) 2014 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.07) 2013 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.07) 2012 Modelled IHME, GBD 2019 (accessed 2022)
0.06 (0.04 - 0.07) 2011 Modelled IHME, GBD 2019 (accessed 2022)
0.06 (0.04 - 0.07) 2010 Modelled IHME, GBD 2019 (accessed 2022)
0.06 (0.04 - 0.07) 2009 Modelled IHME, GBD 2019 (accessed 2022)
0.06 (0.04 - 0.07) 2008 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.07) 2007 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.07) 2006 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.07) 2005 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.07) 2004 Modelled IHME, GBD 2019 (accessed 2022)
0.05 (0.04 - 0.07) 2003 Modelled IHME, GBD 2019 (accessed 2022)
0.06 (0.04 - 0.07) 2002 Modelled IHME, GBD 2019 (accessed 2022)
0.06 (0.04 - 0.08) 2001 Modelled IHME, GBD 2019 (accessed 2022)
0.06 (0.04 - 0.08) 2000 Modelled IHME, GBD 2019 (accessed 2022)
0.06 (0.05 - 0.08) 1999 Modelled IHME, GBD 2019 (accessed 2022)
0.07 (0.05 - 0.09) 1998 Modelled IHME, GBD 2019 (accessed 2022)
0.07 (0.05 - 0.09) 1997 Modelled IHME, GBD 2019 (accessed 2022)
0.07 (0.06 - 0.10) 1996 Modelled IHME, GBD 2019 (accessed 2022)
0.08 (0.06 - 0.11) 1995 Modelled IHME, GBD 2019 (accessed 2022)
0.09 (0.07 - 0.12) 1994 Modelled IHME, GBD 2019 (accessed 2022)
0.11 (0.08 - 0.14) 1993 Modelled IHME, GBD 2019 (accessed 2022)
0.13 (0.10 - 0.17) 1992 Modelled IHME, GBD 2019 (accessed 2022)
0.16 (0.12 - 0.20) 1991 Modelled IHME, GBD 2019 (accessed 2022)
0.19 (0.14 - 0.24) 1990 Modelled IHME, GBD 2019 (accessed 2022)
0.01 (0.01 - 0.02) 2020 Modelled WHO
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Technical notes

Number of people living with chronic HBV

National
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Value Year Type Source
875,000 (654,000 - 1,033,000) 2016 Modelled Razavi-Shearer et al, 2018
862,000 2016 Survey/reported Patel EU, Thio CL, Boon D, Thomas DL, Tobian AAR
2,400,000 2016 Survey/reported Wong, R.J. et al
1,108,930 (968,729 - 1,253,410) 2019 Modelled IHME, GBD 2019 (accessed 2020)
1,139,350 (995,333 - 1,285,450) 2019 Modelled IHME, GBD 2019 (accessed 2022)
1,138,660 (996,177 - 1,285,030) 2018 Modelled IHME, GBD 2019 (accessed 2022)
1,140,310 (997,996 - 1,283,890) 2017 Modelled IHME, GBD 2019 (accessed 2022)
1,172,620 (1,028,550 - 1,312,930) 2016 Modelled IHME, GBD 2019 (accessed 2022)
1,203,950 (1,054,600 - 1,344,410) 2015 Modelled IHME, GBD 2019 (accessed 2022)
1,210,520 (1,062,790 - 1,352,820) 2014 Modelled IHME, GBD 2019 (accessed 2022)
1,226,200 (1,079,990 - 1,370,680) 2013 Modelled IHME, GBD 2019 (accessed 2022)
1,244,380 (1,098,100 - 1,392,220) 2012 Modelled IHME, GBD 2019 (accessed 2022)
1,258,920 (1,109,190 - 1,409,830) 2011 Modelled IHME, GBD 2019 (accessed 2022)
1,264,050 (1,115,330 - 1,417,690) 2010 Modelled IHME, GBD 2019 (accessed 2022)
1,273,340 (1,122,470 - 1,428,880) 2009 Modelled IHME, GBD 2019 (accessed 2022)
1,297,110 (1,141,020 - 1,456,370) 2008 Modelled IHME, GBD 2019 (accessed 2022)
1,324,450 (1,161,580 - 1,485,660) 2007 Modelled IHME, GBD 2019 (accessed 2022)
1,345,230 (1,176,000 - 1,511,760) 2006 Modelled IHME, GBD 2019 (accessed 2022)
1,350,000 (1,178,460 - 1,518,630) 2005 Modelled IHME, GBD 2019 (accessed 2022)
1,347,300 (1,177,160 - 1,513,260) 2004 Modelled IHME, GBD 2019 (accessed 2022)
1,349,680 (1,179,240 - 1,513,010) 2003 Modelled IHME, GBD 2019 (accessed 2022)
1,353,220 (1,184,700 - 1,516,250) 2002 Modelled IHME, GBD 2019 (accessed 2022)
1,354,100 (1,184,790 - 1,516,640) 2001 Modelled IHME, GBD 2019 (accessed 2022)
1,348,870 (1,181,620 - 1,516,390) 2000 Modelled IHME, GBD 2019 (accessed 2022)
1,347,200 (1,179,820 - 1,512,460) 1999 Modelled IHME, GBD 2019 (accessed 2022)
1,356,070 (1,183,340 - 1,523,440) 1998 Modelled IHME, GBD 2019 (accessed 2022)
1,367,970 (1,193,370 - 1,534,730) 1997 Modelled IHME, GBD 2019 (accessed 2022)
1,375,870 (1,198,600 - 1,544,970) 1996 Modelled IHME, GBD 2019 (accessed 2022)
1,373,270 (1,193,270 - 1,544,810) 1995 Modelled IHME, GBD 2019 (accessed 2022)
1,365,560 (1,187,140 - 1,536,170) 1994 Modelled IHME, GBD 2019 (accessed 2022)
1,361,670 (1,182,960 - 1,536,740) 1993 Modelled IHME, GBD 2019 (accessed 2022)
1,360,050 (1,181,530 - 1,541,050) 1992 Modelled IHME, GBD 2019 (accessed 2022)
1,359,260 (1,179,500 - 1,545,610) 1991 Modelled IHME, GBD 2019 (accessed 2022)
1,358,120 (1,178,630 - 1,545,100) 1990 Modelled IHME, GBD 2019 (accessed 2022)
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Number of new cases of HBV

National
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Value Year Type Source
20,700 (11,800 - 50,800) 2019 Survey/reported US CDC: Viral Hepatitis Surveillance Report 2019 - Hepatitis B

HBV-related death rate

National
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Value (per 100,000) Year Type Source
0.5 2014 Survey/reported US CDC
0.45 2016 Survey/reported US CDC
0.46 2017 Survey/reported US CDC
0.52 2010 Survey/reported US CDC
0.51 2011 Survey/reported US CDC
0.51 2012 Survey/reported US CDC
0.53 2013 Survey/reported US CDC
0.46 2015 Survey/reported US CDC
0.42 2019 Survey/reported US CDC: Viral Hepatitis Surveillance Report 2019 - Hepatitis B
1.37 (1.18 - 1.58) 2019 Modelled IHME, GBD 2019 (accessed 2020)
0.98 (0.88 - 1.10) 1990 Modelled IHME, GBD 2019 (accessed 2022)
0.97 (0.87 - 1.06) 1991 Modelled IHME, GBD 2019 (accessed 2022)
0.96 (0.86 - 1.05) 1992 Modelled IHME, GBD 2019 (accessed 2022)
0.97 (0.88 - 1.06) 1993 Modelled IHME, GBD 2019 (accessed 2022)
0.99 (0.90 - 1.07) 1995 Modelled IHME, GBD 2019 (accessed 2022)
0.97 (0.89 - 1.06) 1994 Modelled IHME, GBD 2019 (accessed 2022)
1 (0.91 - 1.08) 1996 Modelled IHME, GBD 2019 (accessed 2022)
1.01 (0.92 - 1.10) 1997 Modelled IHME, GBD 2019 (accessed 2022)
1.03 (0.95 - 1.12) 1998 Modelled IHME, GBD 2019 (accessed 2022)
1.06 (0.97 - 1.15) 1999 Modelled IHME, GBD 2019 (accessed 2022)
1.08 (0.99 - 1.18) 2000 Modelled IHME, GBD 2019 (accessed 2022)
1.12 (1.02 - 1.22) 2002 Modelled IHME, GBD 2019 (accessed 2022)
1.1 (1.01 - 1.20) 2001 Modelled IHME, GBD 2019 (accessed 2022)
1.13 (1.03 - 1.23) 2003 Modelled IHME, GBD 2019 (accessed 2022)
1.13 (1.03 - 1.23) 2004 Modelled IHME, GBD 2019 (accessed 2022)
1.16 (1.06 - 1.26) 2005 Modelled IHME, GBD 2019 (accessed 2022)
1.18 (1.08 - 1.28) 2006 Modelled IHME, GBD 2019 (accessed 2022)
1.19 (1.08 - 1.29) 2007 Modelled IHME, GBD 2019 (accessed 2022)
1.2 (1.10 - 1.32) 2008 Modelled IHME, GBD 2019 (accessed 2022)
1.22 (1.11 - 1.34) 2009 Modelled IHME, GBD 2019 (accessed 2022)
1.24 (1.12 - 1.36) 2010 Modelled IHME, GBD 2019 (accessed 2022)
1.27 (1.15 - 1.40) 2011 Modelled IHME, GBD 2019 (accessed 2022)
1.31 (1.18 - 1.45) 2012 Modelled IHME, GBD 2019 (accessed 2022)
1.35 (1.22 - 1.50) 2013 Modelled IHME, GBD 2019 (accessed 2022)
1.39 (1.25 - 1.54) 2014 Modelled IHME, GBD 2019 (accessed 2022)
1.4 (1.25 - 1.57) 2016 Modelled IHME, GBD 2019 (accessed 2022)
1.34 (1.17 - 1.52) 2017 Modelled IHME, GBD 2019 (accessed 2022)
1.43 (1.28 - 1.59) 2015 Modelled IHME, GBD 2019 (accessed 2022)
1.36 (1.18 - 1.55) 2018 Modelled IHME, GBD 2019 (accessed 2022)
1.37 (1.18 - 1.58) 2019 Modelled IHME, GBD 2019 (accessed 2022)
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HBV-related deaths

National
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Value Year Type Source
11,522 2016 Modelled WHO
1,662 2019 Survey/reported US CDC: Viral Hepatitis Surveillance Report 2019 - Hepatitis B
2,498 (2,240 - 2,778) 1990 Modelled IHME, GBD 2019 (accessed 2022)
2,475 (2,228 - 2,727) 1991 Modelled IHME, GBD 2019 (accessed 2022)
2,479 (2,241 - 2,724) 1992 Modelled IHME, GBD 2019 (accessed 2022)
2,576 (2,351 - 2,803) 1994 Modelled IHME, GBD 2019 (accessed 2022)
2,639 (2,413 - 2,869) 1995 Modelled IHME, GBD 2019 (accessed 2022)
2,533 (2,299 - 2,770) 1993 Modelled IHME, GBD 2019 (accessed 2022)
2,688 (2,461 - 2,917) 1996 Modelled IHME, GBD 2019 (accessed 2022)
2,752 (2,520 - 2,989) 1997 Modelled IHME, GBD 2019 (accessed 2022)
2,845 (2,611 - 3,087) 1998 Modelled IHME, GBD 2019 (accessed 2022)
2,947 (2,705 - 3,193) 1999 Modelled IHME, GBD 2019 (accessed 2022)
3,041 (2,791 - 3,302) 2000 Modelled IHME, GBD 2019 (accessed 2022)
3,196 (2,930 - 3,479) 2002 Modelled IHME, GBD 2019 (accessed 2022)
3,120 (2,858 - 3,393) 2001 Modelled IHME, GBD 2019 (accessed 2022)
3,262 (2,985 - 3,558) 2003 Modelled IHME, GBD 2019 (accessed 2022)
3,292 (3,017 - 3,587) 2004 Modelled IHME, GBD 2019 (accessed 2022)
3,408 (3,118 - 3,714) 2005 Modelled IHME, GBD 2019 (accessed 2022)
3,498 (3,202 - 3,815) 2006 Modelled IHME, GBD 2019 (accessed 2022)
3,569 (3,252 - 3,893) 2007 Modelled IHME, GBD 2019 (accessed 2022)
3,739 (3,397 - 4,099) 2009 Modelled IHME, GBD 2019 (accessed 2022)
3,654 (3,327 - 4,001) 2008 Modelled IHME, GBD 2019 (accessed 2022)
3,965 (3,595 - 4,371) 2011 Modelled IHME, GBD 2019 (accessed 2022)
3,817 (3,459 - 4,201) 2010 Modelled IHME, GBD 2019 (accessed 2022)
4,108 (3,718 - 4,542) 2012 Modelled IHME, GBD 2019 (accessed 2022)
4,261 (3,856 - 4,728) 2013 Modelled IHME, GBD 2019 (accessed 2022)
4,516 (4,023 - 5,073) 2016 Modelled IHME, GBD 2019 (accessed 2022)
4,584 (4,107 - 5,100) 2015 Modelled IHME, GBD 2019 (accessed 2022)
4,423 (3,984 - 4,917) 2014 Modelled IHME, GBD 2019 (accessed 2022)
4,345 (3,813 - 4,935) 2017 Modelled IHME, GBD 2019 (accessed 2022)
4,422 (3,862 - 5,064) 2018 Modelled IHME, GBD 2019 (accessed 2022)
4,486 (3,874 - 5,178) 2019 Modelled IHME, GBD 2019 (accessed 2022)
4,486 (3,874 - 5,178) 2019 Modelled IHME, GBD 2019 (accessed 2020)
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Technical notes

Percent of liver cancer deaths attributable to HBV

National
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Value (%) Year Type Source
4 (3 - 5) 1990 Modelled IHME, GBD 2019 (accessed 2022)
4 (4 - 5) 1991 Modelled IHME, GBD 2019 (accessed 2022)
4 (4 - 5) 1992 Modelled IHME, GBD 2019 (accessed 2022)
4 (4 - 5) 1993 Modelled IHME, GBD 2019 (accessed 2022)
4 (4 - 5) 1994 Modelled IHME, GBD 2019 (accessed 2022)
5 (4 - 5) 1995 Modelled IHME, GBD 2019 (accessed 2022)
5 (4 - 5) 1996 Modelled IHME, GBD 2019 (accessed 2022)
5 (4 - 6) 1997 Modelled IHME, GBD 2019 (accessed 2022)
5 (5 - 6) 1998 Modelled IHME, GBD 2019 (accessed 2022)
6 (5 - 6) 2000 Modelled IHME, GBD 2019 (accessed 2022)
6 (5 - 6) 1999 Modelled IHME, GBD 2019 (accessed 2022)
6 (6 - 7) 2002 Modelled IHME, GBD 2019 (accessed 2022)
6 (5 - 7) 2001 Modelled IHME, GBD 2019 (accessed 2022)
6 (6 - 7) 2003 Modelled IHME, GBD 2019 (accessed 2022)
7 (6 - 8) 2004 Modelled IHME, GBD 2019 (accessed 2022)
7 (6 - 8) 2005 Modelled IHME, GBD 2019 (accessed 2022)
7 (7 - 8) 2006 Modelled IHME, GBD 2019 (accessed 2022)
8 (7 - 9) 2007 Modelled IHME, GBD 2019 (accessed 2022)
8 (7 - 9) 2009 Modelled IHME, GBD 2019 (accessed 2022)
8 (7 - 9) 2008 Modelled IHME, GBD 2019 (accessed 2022)
9 (7 - 10) 2011 Modelled IHME, GBD 2019 (accessed 2022)
8 (7 - 10) 2010 Modelled IHME, GBD 2019 (accessed 2022)
9 (8 - 10) 2012 Modelled IHME, GBD 2019 (accessed 2022)
9 (8 - 10) 2013 Modelled IHME, GBD 2019 (accessed 2022)
9 (8 - 10) 2014 Modelled IHME, GBD 2019 (accessed 2022)
9 (8 - 11) 2015 Modelled IHME, GBD 2019 (accessed 2022)
9 (8 - 11) 2017 Modelled IHME, GBD 2019 (accessed 2022)
9 (8 - 11) 2016 Modelled IHME, GBD 2019 (accessed 2022)
9 (8 - 11) 2018 Modelled IHME, GBD 2019 (accessed 2022)
9 (8 - 11) 2019 Modelled IHME, GBD 2019 (accessed 2022)
12 (10 - 14) 2019 Modelled IHME, GBD 2019 (accessed 2020)
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Technical notes

Coverage of HepB birth dose

Newborns
Download
Value (%) Year Type Source
67 2019 Survey/reported WHO/UNICEF
66 2018 Survey/reported WHO/UNICEF
64 2017 Survey/reported WHO/UNICEF
64 2016 Survey/reported WHO/UNICEF
72 2015 Survey/reported WHO/UNICEF
72 2014 Survey/reported WHO/UNICEF
74 2013 Survey/reported WHO/UNICEF
72 2012 Survey/reported WHO/UNICEF
69 2011 Survey/reported WHO/UNICEF
64 2010 Survey/reported WHO/UNICEF
61 2009 Survey/reported WHO/UNICEF
55 2008 Survey/reported WHO/UNICEF
53 2007 Survey/reported WHO/UNICEF
50 2006 Survey/reported WHO/UNICEF
50 2005 Survey/reported WHO/UNICEF
48 2004 Survey/reported WHO/UNICEF
39 2003 Survey/reported WHO/UNICEF
21 2002 Survey/reported WHO/UNICEF
69 2020 Survey/reported WHO/UNICEF
76 2017 Survey/reported Hill HA et al, 2020
69 2021 Survey/reported WHO/UNICEF
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Coverage of 3-dose hepatitis B vaccine

Infants
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Value (%) Year Type Source
91 2019 Survey/reported WHO/UNICEF
91 2020 Survey/reported WHO/UNICEF
91 2017 Survey/reported Hill HA et al, 2020
91 2021 Survey/reported WHO/UNICEF
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Proportion of persons living with HBV diagnosed

National
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Value (%) Year Type Source
32 2016 Survey/reported U.S. Department of Health and Human Services

Proportion of diagnosed HBV persons receiving appropriate treatment

National
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Value (%) Year Type Source
18 2016 Survey/reported Harris AM et al, 2020

Number of needles/syringes per PWID per year

People who inject drugs (PWID)
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Value Year Type Source
30 (11 - 49) 2016 Survey/reported NASEN, 2015; Wejnert C et al, 2016; Des Jarlais D et al , 2013
Technical notes
HBV National Action Plan
Source:
HBV elimination goal
Source:
Year of HBV elimination goal
2030
Source:
National prevalence survey within the last 5 years
Adopted
Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD…
Estimates of economic burden
Adopted
Toy M et al
System for monitoring testing and treatment
Partially Adopted
Harris, A.M. et al
HepB birth dose policy
Yes
Source: WHO
Year of birth dose introduction
1999
Source: WHO
Recommendations for HBV testing of pregnant women
Adopted
U.S. Department of Health and Human Services
Eligible for HBV generic medicines
Source: MPP
Licensed point-of-care PCR testing to detect HBV
Not Adopted
HBV testing policy
Pregnant women, Risk-based
Source:
HBV testing recommendations for key population (i.e. migrants, foreign-born, etc)
Adopted
US CDC
No patient co-pays for HBsAg testing
Adopted
U.S Department of Health and Human Service
National treatment guidelines exist
Adopted
Terrault, N. A et al
Simplified care: No treatment co-pays
Partially Adopted
Adult HBV vaccination policy for high-risk populations
Adopted
Schillie, S et al
Public budget line for testing and treatment
Adopted
US CDC
HCV National Action Plan
Source:
HCV elimination goal
Source:
Year of HCV elimination goal
2030
Source:
National prevalence survey within the last 5 years
Adopted
Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD…
Estimates of economic burden
Adopted
Roebuck MC, Liberman JN
System for monitoring testing and treatment
Partially Adopted
Isenhour C et al
Recommendations for HCV testing of pregnant women
Adopted
US CDC
Registration of originator HCV DAAs
Adopted
US Food and Drug Administration
Eligible for HCV generic medicines
Source: MPP
Licensed point-of-care PCR testing to detect HCV
Not Adopted
HCV testing policy
Universal
Source:
No patient co-pays for anti-HCV testing
Adopted
U.S Department of Health and Human Service
National treatment guidelines exist
Adopted
AASLD-IDSA
Simplified care: Non-specialists can prescribe treatment
Partially Adopted
Center for Health Law and Policy Innovation, Harvard Law School
Simplified care: No treatment co-pays
Partially Adopted
No fibrosis restrictions
Partially Adopted
Center for Health Law and Policy Innovation, Harvard Law School
No sobriety restrictions
Partially Adopted
Center for Health Law and Policy Innovation, Harvard Law School
National policy for harm reduction for persons who inject drugs
Adopted
Georgetown HIV Policy Lab
National policy for syringe exchange in federal prisons
Not Adopted
Georgetown HIV Policy Lab
At least one needle-syringe exchange program (NSP) operational
Yes
Source: Harm Reduction International
At least one opioid substitution therapy (OST) program operational
Yes
Source: Harm Reduction International
OST in at least one prison
Yes
Source: Harm Reduction International
% of substance use disorder facilities offering hepatitis testing
Many (31-60%)
Source: WHO
Decriminalization of possession of syringes and paraphernalia
Partially Adopted
Public budget line for testing and treatment
Adopted
US CDC

Hepatitis C

Download HCV data

Prevalence of chronic HCV (RNA+/cAg)

National
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Value (%) Year Type Source
1 (0.80 - 1.10) 2016 Survey/reported Hofmeister MG et al, 2019 (Adjusted)
1 (0.80 - 1.20) 2010 Survey/reported Denniston MM et al, 2014 (Unadjusted)
1.3 (1 - 1.50) 2002 Survey/reported Armstrong GL wt al, 2006 (Unadjusted)
0.9 (0.70 - 1.20) 2015 Modelled Blach et al, 2017
0.84 (0.75 - 0.96) 2016 Survey/reported Rosenberg et al, 2018 (Unadjusted)
0.93 2016 Survey/reported Rosenberg et al, 2018 (Adjusted)
1 (0.90 - 1.80) 2014 Modelled Gower et al, 2014
1.25 (1.02 - 1.54) 2019 Modelled IHME, GBD 2019 (accessed 2022)
1.26 (1.02 - 1.55) 2018 Modelled IHME, GBD 2019 (accessed 2022)
1.26 (1.02 - 1.54) 2017 Modelled IHME, GBD 2019 (accessed 2022)
1.23 (1 - 1.51) 2016 Modelled IHME, GBD 2019 (accessed 2022)
1.2 (0.98 - 1.47) 2015 Modelled IHME, GBD 2019 (accessed 2022)
1.19 (0.97 - 1.46) 2014 Modelled IHME, GBD 2019 (accessed 2022)
1.19 (0.97 - 1.46) 2013 Modelled IHME, GBD 2019 (accessed 2022)
1.19 (0.97 - 1.46) 2012 Modelled IHME, GBD 2019 (accessed 2022)
1.19 (0.96 - 1.46) 2011 Modelled IHME, GBD 2019 (accessed 2022)
1.19 (0.96 - 1.46) 2010 Modelled IHME, GBD 2019 (accessed 2022)
1.19 (0.96 - 1.47) 2009 Modelled IHME, GBD 2019 (accessed 2022)
1.2 (0.97 - 1.48) 2008 Modelled IHME, GBD 2019 (accessed 2022)
1.22 (0.98 - 1.50) 2007 Modelled IHME, GBD 2019 (accessed 2022)
1.23 (0.99 - 1.52) 2006 Modelled IHME, GBD 2019 (accessed 2022)
1.24 (1 - 1.53) 2005 Modelled IHME, GBD 2019 (accessed 2022)
1.24 (1 - 1.53) 2004 Modelled IHME, GBD 2019 (accessed 2022)
1.24 (0.99 - 1.53) 2003 Modelled IHME, GBD 2019 (accessed 2022)
1.24 (0.99 - 1.53) 2002 Modelled IHME, GBD 2019 (accessed 2022)
1.23 (0.99 - 1.53) 2001 Modelled IHME, GBD 2019 (accessed 2022)
1.23 (0.98 - 1.52) 2000 Modelled IHME, GBD 2019 (accessed 2022)
1.21 (0.97 - 1.50) 1999 Modelled IHME, GBD 2019 (accessed 2022)
1.19 (0.95 - 1.47) 1998 Modelled IHME, GBD 2019 (accessed 2022)
1.16 (0.93 - 1.44) 1997 Modelled IHME, GBD 2019 (accessed 2022)
1.13 (0.91 - 1.41) 1996 Modelled IHME, GBD 2019 (accessed 2022)
1.12 (0.90 - 1.39) 1995 Modelled IHME, GBD 2019 (accessed 2022)
1.1 (0.88 - 1.37) 1994 Modelled IHME, GBD 2019 (accessed 2022)
1.09 (0.87 - 1.36) 1993 Modelled IHME, GBD 2019 (accessed 2022)
1.08 (0.87 - 1.34) 1992 Modelled IHME, GBD 2019 (accessed 2022)
1.06 (0.85 - 1.32) 1991 Modelled IHME, GBD 2019 (accessed 2022)
1.05 (0.84 - 1.31) 1990 Modelled IHME, GBD 2019 (accessed 2022)
1.18 (0.95 - 1.45) 2019 Modelled IHME, GBD 2019 (accessed 2020)
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Women of childbearing age (15–49 years)
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Value (%) Year Type Source
0.49 (0.37 - 0.64) 2019 Modelled Dugan et al., 2021
Technical notes

Prevalence of anti-HCV

National
Download
Value (%) Year Type Source
1.7 (1.40 - 2) 2016 Survey/reported Hofmeister MG et al, 2019 (Adjusted)
1.3 (1.20 - 1.50) 2010 Survey/reported Denniston MM et al, 2014 (Unadjusted)
1.6 (1.30 - 1.90) 2002 Survey/reported Armstrong GL wt al, 2006 (Unadjusted)
1.8 (1.50 - 2.30) 1994 Survey/reported Alter MJ et al, 1999 (Unadjusted)
1.9 (1.50 - 2.50) 2002 Survey/reported Ditah et al, 2014
1.3 (0.90 - 1.80) 2006 Survey/reported Ditah et al, 2014
1.48 2019 Modelled Jin et al. 2017
1.3 (1.20 - 2.40) 2014 Modelled Gower et al, 2014
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Men who have sex with men (MSM) Living with HIV
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Value (%) Year Type Source
9.7 (7.10 - 12.60) 2019 Modelled Jin et al. 2017
People who inject drugs (PWID)
Download
Value (%) Year Type Source
53.1 (38.10 - 68) 2016 Modelled Degenhardt L et al, 2017
Men who have sex with men (MSM)
Download
Value (%) Year Type Source
4.4 2019 Modelled Jin et al. 2017
Technical notes

Number of people living with chronic HCV (RNA+/cAg)

National
Download
Value Year Type Source
2,936,000 (2,231,000 - 3,826,000) 2015 Modelled Blach et al, 2017
2,400,000 2016 Survey/reported US CDC
2,519,250 (2,019,580 - 3,149,250) 1990 Modelled IHME, GBD 2019 (accessed 2022)
2,567,040 (2,059,080 - 3,206,460) 1991 Modelled IHME, GBD 2019 (accessed 2022)
2,620,180 (2,107,400 - 3,268,480) 1992 Modelled IHME, GBD 2019 (accessed 2022)
2,676,400 (2,154,060 - 3,340,820) 1993 Modelled IHME, GBD 2019 (accessed 2022)
2,732,710 (2,198,420 - 3,399,680) 1994 Modelled IHME, GBD 2019 (accessed 2022)
2,789,860 (2,248,100 - 3,464,760) 1995 Modelled IHME, GBD 2019 (accessed 2022)
2,860,910 (2,305,140 - 3,551,960) 1996 Modelled IHME, GBD 2019 (accessed 2022)
2,954,980 (2,380,770 - 3,673,490) 1997 Modelled IHME, GBD 2019 (accessed 2022)
3,056,730 (2,463,570 - 3,801,140) 1998 Modelled IHME, GBD 2019 (accessed 2022)
3,148,740 (2,535,630 - 3,911,860) 1999 Modelled IHME, GBD 2019 (accessed 2022)
3,216,480 (2,589,140 - 3,993,100) 2000 Modelled IHME, GBD 2019 (accessed 2022)
3,261,100 (2,626,960 - 4,034,700) 2001 Modelled IHME, GBD 2019 (accessed 2022)
3,300,340 (2,660,860 - 4,078,900) 2002 Modelled IHME, GBD 2019 (accessed 2022)
3,335,740 (2,690,850 - 4,127,690) 2003 Modelled IHME, GBD 2019 (accessed 2022)
3,367,660 (2,721,080 - 4,172,570) 2004 Modelled IHME, GBD 2019 (accessed 2022)
3,398,480 (2,749,450 - 4,216,270) 2005 Modelled IHME, GBD 2019 (accessed 2022)
3,414,710 (2,765,800 - 4,236,680) 2006 Modelled IHME, GBD 2019 (accessed 2022)
3,414,940 (2,768,060 - 4,229,390) 2007 Modelled IHME, GBD 2019 (accessed 2022)
3,410,470 (2,766,150 - 4,215,210) 2008 Modelled IHME, GBD 2019 (accessed 2022)
3,411,690 (2,770,420 - 4,208,510) 2009 Modelled IHME, GBD 2019 (accessed 2022)
3,432,700 (2,793,440 - 4,225,520) 2010 Modelled IHME, GBD 2019 (accessed 2022)
3,466,620 (2,819,040 - 4,264,040) 2011 Modelled IHME, GBD 2019 (accessed 2022)
3,502,940 (2,851,980 - 4,303,690) 2012 Modelled IHME, GBD 2019 (accessed 2022)
3,542,590 (2,884,740 - 4,345,020) 2013 Modelled IHME, GBD 2019 (accessed 2022)
3,585,500 (2,921,770 - 4,393,670) 2014 Modelled IHME, GBD 2019 (accessed 2022)
3,634,680 (2,947,680 - 4,451,870) 2015 Modelled IHME, GBD 2019 (accessed 2022)
3,749,680 (3,048,880 - 4,594,180) 2016 Modelled IHME, GBD 2019 (accessed 2022)
3,864,380 (3,141,540 - 4,732,270) 2017 Modelled IHME, GBD 2019 (accessed 2022)
3,899,850 (3,171,200 - 4,776,430) 2018 Modelled IHME, GBD 2019 (accessed 2022)
3,900,550 (3,170,570 - 4,781,980) 2019 Modelled IHME, GBD 2019 (accessed 2022)
3,865,100 (3,131,620 - 4,746,640) 2019 Modelled IHME, GBD 2019 (accessed 2020)
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Women of childbearing age (15–49 years)
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Value Year Type Source
368,000 (280,000 - 480,000) 2019 Modelled Dugan et al., 2021

Number of new cases of HCV

National
Download
Value Year Type Source
57,500 (45,500 - 196,000) 2019 Survey/reported US CDC: Viral Hepatitis Surveillance Report 2019 - Hepatitis C

Rate of new HCV cases

American Indian/Alaska Native
Download
Value (Number of new cases per 100,000 persons) Year Type Source
3.6 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
3.6 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
2.9 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
3.1 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
1.7 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
1.3 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
1.7 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
2 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
1.08 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0.5 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0.46 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
0.5 2008 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2008
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Asian/Pacific Islander
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Value (Number of new cases per 100,000 persons) Year Type Source
0.2 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
0.2 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
0.1 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
0.1 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.1 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.1 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
0.1 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
0.1 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
0.05 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0.04 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
0.04 2008 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2008
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Black, non-Hispanic
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Value (Number of new cases per 100,000 persons) Year Type Source
0.7 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
0.6 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
0.5 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
0.3 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.3 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.2 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
0.2 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
0.2 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
0.14 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0.12 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0.1 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
0.2 2008 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2008
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Hispanic
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Value (Number of new cases per 100,000 persons) Year Type Source
0.6 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
0.5 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
0.4 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
0.4 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.3 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.2 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
0.2 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
0.2 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
0.17 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0.16 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0.1 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
0.1 2008 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2008
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White, non-Hispanic
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Value (Number of new cases per 100,000 persons) Year Type Source
1.4 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
1.3 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
1.2 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
1.1 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.9 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.8 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
0.8 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
0.6 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
0.47 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0.32 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0.3 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
0.3 2008 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2008
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0-19 year olds
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Value (Number of new cases per 100,000 persons) Year Type Source
0.1 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
0.1 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
0.1 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
0.1 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.1 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.1 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
0.1 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
0.11 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
0.1 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
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Less than 15 years old
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Value (Number of new cases per 100,000 persons) Year Type Source
0 2008 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2008
20-29 year olds
Download
Value (Number of new cases per 100,000 persons) Year Type Source
2.9 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
3.1 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
2.8 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
2.7 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
2.4 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
2.2 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
2 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
1.73 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
1.18 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0.8 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0.7 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
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25-39 year olds
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Value (Number of new cases per 100,000 persons) Year Type Source
0.5 2008 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2008
30-39 year olds
Download
Value (Number of new cases per 100,000 persons) Year Type Source
3.2 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
2.6 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
2.3 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
2.2 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
1.7 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
1.7 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
1.3 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
1.1 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
0.8 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0.6 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0.5 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
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15-24 year olds
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Value (Number of new cases per 100,000 persons) Year Type Source
0.4 2008 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2008
50-59 year olds
Download
Value (Number of new cases per 100,000 persons) Year Type Source
1.1 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
0.9 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
0.8 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
0.6 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.6 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.4 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
0.5 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
0.4 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
0.3 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0.3 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0.3 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
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40-49 year olds
Download
Value (Number of new cases per 100,000 persons) Year Type Source
1.7 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
1.3 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
1.1 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
1.2 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.9 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.7 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
0.7 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
0.6 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
0.5 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0.4 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0.5 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
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Over 40 years old
Download
Value (Number of new cases per 100,000 persons) Year Type Source
0.3 2008 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2008
Over 60 years old
Download
Value (Number of new cases per 100,000 persons) Year Type Source
0.5 2019 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2019
0.4 2018 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2018
0.3 2017 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2017
0.2 2016 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.1 2015 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2016
0.1 2014 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2014
0.1 2013 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2013
0.1 2012 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2012
0.07 2011 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2011
0 2010 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2010
0.04 2009 Survey/reported US CDC. Viral Hepatitis Surveillance Report 2009
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Technical notes

HCV-related death rate

National
Download
Value (Deaths per 100,000) Year Type Source
4.45 2016 Survey/reported US CDC, 2016
4.91 2015 Survey/reported US CDC, 2020
5.01 2014 Survey/reported US CDC, 2019
5.03 2013 Survey/reported US CDC, 2018
4.96 2012 Survey/reported US CDC, 2017
3.33 2019 Survey/reported US CDC: Viral Hepatitis Surveillance Report 2019 - Hepatitis C
11.9 (10.80 - 13.10) 2019 Modelled IHME, GBD 2019 (accessed 2020)
6.68 (6.07 - 7.37) 1990 Modelled IHME, GBD 2019 (accessed 2022)
6.8 (6.24 - 7.43) 1991 Modelled IHME, GBD 2019 (accessed 2022)
6.95 (6.41 - 7.53) 1992 Modelled IHME, GBD 2019 (accessed 2022)
7.23 (6.70 - 7.80) 1993 Modelled IHME, GBD 2019 (accessed 2022)
7.4 (6.87 - 7.95) 1994 Modelled IHME, GBD 2019 (accessed 2022)
7.56 (7.03 - 8.13) 1995 Modelled IHME, GBD 2019 (accessed 2022)
7.63 (7.10 - 8.20) 1996 Modelled IHME, GBD 2019 (accessed 2022)
7.75 (7.23 - 8.33) 1997 Modelled IHME, GBD 2019 (accessed 2022)
7.94 (7.39 - 8.53) 1998 Modelled IHME, GBD 2019 (accessed 2022)
8.17 (7.63 - 8.78) 1999 Modelled IHME, GBD 2019 (accessed 2022)
8.4 (7.87 - 9.01) 2000 Modelled IHME, GBD 2019 (accessed 2022)
8.84 (8.27 - 9.48) 2002 Modelled IHME, GBD 2019 (accessed 2022)
8.62 (8.08 - 9.25) 2001 Modelled IHME, GBD 2019 (accessed 2022)
9 (8.41 - 9.66) 2003 Modelled IHME, GBD 2019 (accessed 2022)
9.01 (8.41 - 9.68) 2004 Modelled IHME, GBD 2019 (accessed 2022)
9.24 (8.62 - 9.95) 2005 Modelled IHME, GBD 2019 (accessed 2022)
9.4 (8.76 - 10.12) 2006 Modelled IHME, GBD 2019 (accessed 2022)
9.54 (8.88 - 10.27) 2007 Modelled IHME, GBD 2019 (accessed 2022)
9.77 (9.09 - 10.54) 2008 Modelled IHME, GBD 2019 (accessed 2022)
10.14 (9.40 - 10.92) 2010 Modelled IHME, GBD 2019 (accessed 2022)
9.99 (9.28 - 10.78) 2009 Modelled IHME, GBD 2019 (accessed 2022)
10.44 (9.69 - 11.24) 2011 Modelled IHME, GBD 2019 (accessed 2022)
10.67 (9.88 - 11.51) 2012 Modelled IHME, GBD 2019 (accessed 2022)
10.89 (10.09 - 11.78) 2013 Modelled IHME, GBD 2019 (accessed 2022)
11.14 (10.32 - 12.07) 2014 Modelled IHME, GBD 2019 (accessed 2022)
11.4 (10.55 - 12.37) 2015 Modelled IHME, GBD 2019 (accessed 2022)
11.73 (10.77 - 12.76) 2016 Modelled IHME, GBD 2019 (accessed 2022)
11.72 (10.61 - 12.91) 2017 Modelled IHME, GBD 2019 (accessed 2022)
11.85 (10.73 - 13.07) 2018 Modelled IHME, GBD 2019 (accessed 2022)
11.94 (10.83 - 13.15) 2019 Modelled IHME, GBD 2019 (accessed 2022)
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Technical notes

HCV-related deaths

National
Download
Value Year Type Source
21,698 2016 Modelled WHO
14,242 2019 Survey/reported US CDC: Viral Hepatitis Surveillance Report 2019 - Hepatitis C
39,158 (35,520 - 43,124) 2019 Modelled IHME, GBD 2019 (accessed 2022)
39,158 (35,520 - 43,124) 2019 Modelled IHME, GBD 2019 (accessed 2020)
38,668 (35,028 - 42,654) 2018 Modelled IHME, GBD 2019 (accessed 2022)
38,054 (34,421 - 41,900) 2017 Modelled IHME, GBD 2019 (accessed 2022)
37,842 (34,759 - 41,187) 2016 Modelled IHME, GBD 2019 (accessed 2022)
36,565 (33,841 - 39,660) 2015 Modelled IHME, GBD 2019 (accessed 2022)
35,460 (32,872 - 38,434) 2014 Modelled IHME, GBD 2019 (accessed 2022)
34,425 (31,893 - 37,241) 2013 Modelled IHME, GBD 2019 (accessed 2022)
33,475 (31,022 - 36,115) 2012 Modelled IHME, GBD 2019 (accessed 2022)
32,530 (30,185 - 35,022) 2011 Modelled IHME, GBD 2019 (accessed 2022)
31,333 (29,056 - 33,738) 2010 Modelled IHME, GBD 2019 (accessed 2022)
30,611 (28,418 - 33,016) 2009 Modelled IHME, GBD 2019 (accessed 2022)
29,671 (27,590 - 31,990) 2008 Modelled IHME, GBD 2019 (accessed 2022)
28,701 (26,694 - 30,881) 2007 Modelled IHME, GBD 2019 (accessed 2022)
27,985 (26,076 - 30,138) 2006 Modelled IHME, GBD 2019 (accessed 2022)
27,242 (25,403 - 29,330) 2005 Modelled IHME, GBD 2019 (accessed 2022)
26,287 (24,541 - 28,240) 2004 Modelled IHME, GBD 2019 (accessed 2022)
26,004 (24,309 - 27,918) 2003 Modelled IHME, GBD 2019 (accessed 2022)
25,293 (23,674 - 27,122) 2002 Modelled IHME, GBD 2019 (accessed 2022)
24,439 (22,913 - 26,212) 2001 Modelled IHME, GBD 2019 (accessed 2022)
23,578 (22,096 - 25,300) 2000 Modelled IHME, GBD 2019 (accessed 2022)
22,700 (21,193 - 24,409) 1999 Modelled IHME, GBD 2019 (accessed 2022)
21,850 (20,334 - 23,461) 1998 Modelled IHME, GBD 2019 (accessed 2022)
21,121 (19,696 - 22,687) 1997 Modelled IHME, GBD 2019 (accessed 2022)
20,584 (19,155 - 22,118) 1996 Modelled IHME, GBD 2019 (accessed 2022)
20,201 (18,781 - 21,711) 1995 Modelled IHME, GBD 2019 (accessed 2022)
19,577 (18,175 - 21,045) 1994 Modelled IHME, GBD 2019 (accessed 2022)
18,940 (17,555 - 20,435) 1993 Modelled IHME, GBD 2019 (accessed 2022)
18,010 (16,624 - 19,510) 1992 Modelled IHME, GBD 2019 (accessed 2022)
17,433 (16,011 - 19,047) 1991 Modelled IHME, GBD 2019 (accessed 2022)
16,950 (15,387 - 18,693) 1990 Modelled IHME, GBD 2019 (accessed 2022)
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Technical notes

Percent of liver cancer deaths attributable to HCV

National
Download
Value (%) Year Type Source
11 (10 - 13) 1990 Modelled IHME, GBD 2019 (accessed 2022)
12 (11 - 13) 1991 Modelled IHME, GBD 2019 (accessed 2022)
12 (11 - 14) 1992 Modelled IHME, GBD 2019 (accessed 2022)
14 (13 - 15) 1995 Modelled IHME, GBD 2019 (accessed 2022)
13 (12 - 15) 1994 Modelled IHME, GBD 2019 (accessed 2022)
13 (12 - 14) 1993 Modelled IHME, GBD 2019 (accessed 2022)
15 (13 - 16) 1996 Modelled IHME, GBD 2019 (accessed 2022)
15 (14 - 17) 1997 Modelled IHME, GBD 2019 (accessed 2022)
16 (15 - 18) 1998 Modelled IHME, GBD 2019 (accessed 2022)
17 (15 - 18) 1999 Modelled IHME, GBD 2019 (accessed 2022)
18 (16 - 19) 2000 Modelled IHME, GBD 2019 (accessed 2022)
18 (16 - 20) 2001 Modelled IHME, GBD 2019 (accessed 2022)
19 (17 - 20) 2002 Modelled IHME, GBD 2019 (accessed 2022)
21 (19 - 22) 2004 Modelled IHME, GBD 2019 (accessed 2022)
20 (18 - 21) 2003 Modelled IHME, GBD 2019 (accessed 2022)
22 (20 - 23) 2005 Modelled IHME, GBD 2019 (accessed 2022)
23 (21 - 25) 2006 Modelled IHME, GBD 2019 (accessed 2022)
25 (23 - 27) 2008 Modelled IHME, GBD 2019 (accessed 2022)
26 (24 - 28) 2009 Modelled IHME, GBD 2019 (accessed 2022)
24 (22 - 26) 2007 Modelled IHME, GBD 2019 (accessed 2022)
27 (25 - 30) 2010 Modelled IHME, GBD 2019 (accessed 2022)
28 (25 - 31) 2011 Modelled IHME, GBD 2019 (accessed 2022)
29 (26 - 31) 2012 Modelled IHME, GBD 2019 (accessed 2022)
29 (26 - 32) 2013 Modelled IHME, GBD 2019 (accessed 2022)
30 (27 - 33) 2014 Modelled IHME, GBD 2019 (accessed 2022)
31 (28 - 34) 2016 Modelled IHME, GBD 2019 (accessed 2022)
31 (27 - 34) 2017 Modelled IHME, GBD 2019 (accessed 2022)
31 (28 - 34) 2015 Modelled IHME, GBD 2019 (accessed 2022)
31 (27 - 35) 2018 Modelled IHME, GBD 2019 (accessed 2022)
31 (27 - 36) 2019 Modelled IHME, GBD 2019 (accessed 2022)
39 (35 - 43) 2019 Modelled IHME, GBD 2019 (accessed 2020)
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Technical notes

Number of persons initiating HCV treatment

National
Download
Value Year Type Source
109,096 2014 Survey/reported Teshale et al, 2022
164,232 2015 Survey/reported Teshale et al, 2022
134,285 2016 Survey/reported Teshale et al, 2022
114,419 2017 Survey/reported Teshale et al, 2022
122,664 2018 Survey/reported Teshale et al, 2022
114,893 2019 Survey/reported Teshale et al, 2022
83,740 2020 Survey/reported Teshale et al, 2022
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Demographic breakdown of persons treated for HCV

Females (2014-2020)
Download
Value (%) Year Type Source
39.2 2020 Survey/reported Teshale et al, 2022
Males (2014-2020)
Download
Value (%) Year Type Source
59.6 2020 Survey/reported Teshale et al, 2022
Persons born after 1965
Download
Value (%) Year Type Source
17.4 2014 Survey/reported Teshale et al, 2022
51.3 2020 Survey/reported Teshale et al, 2022
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Persons born during 1945–1965
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Value (%) Year Type Source
73.6 2014 Survey/reported Teshale et al, 2022
46.3 2020 Survey/reported Teshale et al, 2022
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Number of needles/syringes per PWID per year

People who inject drugs (PWID)
Download
Value Year Type Source
30 (11 - 49) 2016 Survey/reported NASEN, 2015; Wejnert C et al, 2016; Des Jarlais D et al , 2013
Technical notes

Proportion of persons living with HCV diagnosed

National
Download
Value (%) Year Type Source
60 2016 Survey/reported U.S. Department of Health and Human Services

Proportion of persons living with HCV who have cleared HCV infection

National
Download
Value (%) Year Type Source
43 2016 Survey/reported U.S. Department of Health and Human Services
HBV National Action Plan
Source:
HBV elimination goal
Source:
Year of HBV elimination goal
2030
Source:
National prevalence survey within the last 5 years
Adopted
Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD…
Estimates of economic burden
Adopted
Toy M et al
System for monitoring testing and treatment
Partially Adopted
Harris, A.M. et al
HepB birth dose policy
Yes
Source: WHO
Year of birth dose introduction
1999
Source: WHO
Recommendations for HBV testing of pregnant women
Adopted
U.S. Department of Health and Human Services
Eligible for HBV generic medicines
Source: MPP
Licensed point-of-care PCR testing to detect HBV
Not Adopted
HBV testing policy
Pregnant women, Risk-based
Source:
HBV testing recommendations for key population (i.e. migrants, foreign-born, etc)
Adopted
US CDC
No patient co-pays for HBsAg testing
Adopted
U.S Department of Health and Human Service
National treatment guidelines exist
Adopted
Terrault, N. A et al
Simplified care: No treatment co-pays
Partially Adopted
Adult HBV vaccination policy for high-risk populations
Adopted
Schillie, S et al
Public budget line for testing and treatment
Adopted
US CDC
HCV National Action Plan
Source:
HCV elimination goal
Source:
Year of HCV elimination goal
2030
Source:
National prevalence survey within the last 5 years
Adopted
Division of Viral Hepatitis, National Center for HIV/AIDS, Viral Hepatitis, STD…
Estimates of economic burden
Adopted
Roebuck MC, Liberman JN
System for monitoring testing and treatment
Partially Adopted
Isenhour C et al
Recommendations for HCV testing of pregnant women
Adopted
US CDC
Registration of originator HCV DAAs
Adopted
US Food and Drug Administration
Eligible for HCV generic medicines
Source: MPP
Licensed point-of-care PCR testing to detect HCV
Not Adopted
HCV testing policy
Universal
Source:
No patient co-pays for anti-HCV testing
Adopted
U.S Department of Health and Human Service
National treatment guidelines exist
Adopted
AASLD-IDSA
Simplified care: Non-specialists can prescribe treatment
Partially Adopted
Center for Health Law and Policy Innovation, Harvard Law School
Simplified care: No treatment co-pays
Partially Adopted
No fibrosis restrictions
Partially Adopted
Center for Health Law and Policy Innovation, Harvard Law School
No sobriety restrictions
Partially Adopted
Center for Health Law and Policy Innovation, Harvard Law School
National policy for harm reduction for persons who inject drugs
Adopted
Georgetown HIV Policy Lab
National policy for syringe exchange in federal prisons
Not Adopted
Georgetown HIV Policy Lab
At least one needle-syringe exchange program (NSP) operational
Yes
Source: Harm Reduction International
At least one opioid substitution therapy (OST) program operational
Yes
Source: Harm Reduction International
OST in at least one prison
Yes
Source: Harm Reduction International
% of substance use disorder facilities offering hepatitis testing
Many (31-60%)
Source: WHO
Decriminalization of possession of syringes and paraphernalia
Partially Adopted
Public budget line for testing and treatment
Adopted
US CDC

Overview

HBV elimination goal
Year of goal
2030
HCV elimination goal
Year of goal
2030

Prevalence (national)

Modelled

HBV (HBsAg+)
0.37 (%)
2019
(0.32 - 0.41(%))
IHME, GBD 2019 (accessed 2022)
HCV (RNA/cAg+)
1.18 (%)
2019
(0.95 - 1.45(%))
IHME, GBD 2019 (accessed 2020)

Survey/surveillance

HBV (HBsAg+)
0.3 (%)
2012
(0.2 - 0.4(%))
Roberts H et al, 2016
HCV (anti-HCV)
1.7 (%)
2016
(1.4 - 2(%))
Hofmeister MG et al, 2019 (Adjusted)

Hepatitis related deaths (national)

Modelled

HBV
4,486
2019
(3,874 - 5,178)
IHME, GBD 2019 (accessed 2022)

Survey/surveillance

HBV
1,662
2019
US CDC: Viral Hepatitis Surveillance Report 2019 - Hepatitis B
HBV chart

Modelled

HCV
39,158
2019
(35,520 - 43,124)
IHME, GBD 2019 (accessed 2022)

Survey/surveillance

HCV
14,242
2019
US CDC: Viral Hepatitis Surveillance Report 2019 - Hepatitis C
HCV chart

Prevalence < 5

HBV
0.01 (%)
2020, latest modelled
(0.01 - 0.02(%))
WHO

Prevalence PWID

HCV
53.10 (%)
2016, latest modelled
(38.10 - 68(%))
Degenhardt L et al, 2017

Birth dose vaccination coverage (national)

Survey/surveillance

HBV
69 (%)
2021
WHO/UNICEF

No. of syringes/PWID/year

Survey/surveillance

HCV
30
2016
(11 - 49)
NASEN, 2015; Wejnert C et al, 2016; Des Jarlais D et al , 2013
Eligible for HBV generic medicines
Eligible for HCV generic medicines
Download National Hepatitis Elimination Profile (N-HEP)

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Action plan

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Elimination champion

Rachel Gonzalez

Rachel Gonzalez (2021)

It is revolutionary what the Hepatitis C Innovation Team (HIT) did because you're talking about a federal health care system made up of more than 150 medical centers and 1000 sites of care. How do you move this giant ship? We built a community and said these goals really are aspirational, but we believe in the field teams. We believe in their ability to be creative -- to push innovation. . . If you [only] work in [a] safe space, you’ll never find many of the genuine breakthroughs that came out of HIT.

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